Nivolumab (Opdivo®) Subsidized
Buy Nivolumab Online Subsidized.Cancer specialists can treat many types of cancer, including melanoma, with medications that stimulate the body’s own immune system. This type of treatment, known as immunotherapy, is systemic, which means that the drugs travel through the bloodstream to all parts of your body.Buy Nivolumab Online Subsidized means you can now get full treatment at minimal cost relative to other health care providers.
As a systemic cancer treatment, immunotherapy is effective in fighting metastatic cancer, which has spread from the original tumor to other areas. Nivolumab Subsidized helps shrink tumors, helps patients with advanced melanoma to live longer and decreases the risk of the melanoma coming back after surgery. It is also approved for adjuvant therapy.
What Is Nivolumab (Opdivo)?
- A checkpoint inhibitor, a type of immunotherapy that helps make cancer cells more vulnerable to attack by your body’s own immune system
- An antibody that promotes the tumor-killing effects of T cells (white blood cells that help your body fight disease)
- It is used to treat advanced melanoma that is unresectable or has spread to organs and other parts of the body. In addition, nivolumab is also used as adjuvant therapy, that is, treatment after complete surgical resection of melanoma to reduce the risk of the melanoma returning. To learn more about the use of nivolumab as adjuvant therapy for melanoma.
How much is Nivolumab (Opdivo®) when Subsidized ?
Current checkpoint inhibitors each have a list price near $150,000 a year. A combination of Yervoy and Opdivo, approved by the Food and Drug Administration for advanced or inoperable melanoma, has a cost of $256,000 a year for patients who respond to the treatment.
In the latest trial, the cost of using ipilimumab alone was $158,282 (for a median progress-free survival [PFS] of 2.9 months), the cost of nivolumab alone was $103,220 (for a PFS of 6.9 months), and the cost of the combination was $195,566 (PFS of 11.4 months, nearly four times that seen with ipilimumab alone.
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How Does Nivolumab (Opdivo) Work?
Nivolumab blocks the activity of a molecule called PD-1, a protein that prevents T cells from recognizing and attacking inflamed tissues and cancer cells. PD-1 can trick your immune system into overlooking melanoma cells as normal cells.
Nivolumab triggers your immune system’s response to melanoma by blocking the PD-1 protein on T cells. The drug activates T cells so that they can attack melanoma cells anywhere in your body.
Which Patients May Benefit from Nivolumab (Opdivo)?
Patients with Advanced Melanoma can enjoy Nivolumab (Opdivo®) Subsidized
In 2014, the U.S. Food and Drug Administration (FDA) approved nivolumab to treat patients who have advanced stages of melanoma:
- Stage III that is unresectable (unable to be completely removed by surgery)
- Stage IV, also known as metastatic (melanoma cells that have spread to organs and other parts of the body)
Many experts recommend anti-PD-1 therapy, like nivolumab, as a first-line treatment for patients with advanced melanoma. Patients should speak with their physicians about the risks and benefits of various treatment options as first-line treatment.
Adjuvant Therapy of Melanoma
In December 2017, the U.S. Food and Drug Administration (FDA) approved the use of nivolumab for the treatment melanoma patients with lymph node involvement or metastatic disease who have undergone complete resection. The goal of this use of nivolumab is to reduce the risk of melanoma coming back after surgery. Patients should speak with their physicians about the risk and benefit of various treatment options as adjuvant therapy.
How Is Nivolumab (Opdivo) Given for the Treatment of Advanced Melanoma?
Patients receive nivolumab intravenously (into a blood vein).
- Each dose takes about 60 minutes to complete.
- Patients usually receive nivolumab every two weeks unless their melanoma worsens or they experience unacceptable side effects.
A clear to opalescent, colorless to pale yellow liquid which may contain light (few) particulates.
What Are the Goals of Nivolumab (Opdivo) for the Treatment of Advanced Melanoma?
The goals of using nivolumab include:
- First Controlling melanoma and shrinking tumors anywhere in the body
- Second Treating symptoms of melanoma
- Third Helping patients live longer
Because nivolumab is an antibody that builds up your immune system, it can produce an immunological “memory” in T cells. That means that nivolumab may help your immune system continue to attack melanoma cells even after treatment.
Melanoma treatments, like nivolumab, have side effects, which can sometimes be serious. Patients should talk with their physician to learn more about the side effects of nivolumab and other melanoma treatment options.
What Should I Ask My Doctor About Nivolumab (Opdivo) for the Treatment of Advanced Melanoma?
Not all treatments work for all melanoma patients, because everyone is different.
- Am I eligible for nivolumab?
- What is your experience with nivolumab?
- Is nivolumab a good option for my melanoma treatment?
- Is there an alternative to nivolumab for me?
- How successful has nivolumab been for patients like me?
- What are the side effects of nivolumab?
- Are there any clinical trials for nivolumab that I should consider?
- What are the risks and benefits of the available treatment options?
- What are the goals for my treatment?
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